Vaccitech Says Prime-boost Vaccine Study Data In Women With Low-grade HPV Lesions Is ‘Promising Step In Right Direction’

Vaccitech plc (NASDAQ:VACC) announced topline interim data from the HPV001 Phase 1b/2 clinical trial of VTP-200 in women with low-grade cervical…
  • Vaccitech plc (NASDAQ:VACC) announced topline interim data from the HPV001 Phase 1b/2 clinical trial of VTP-200 in women with low-grade cervical human papillomavirus (HPV) lesions.
  • “These interim data are a promising step in the right direction, and we look forward to seeing the final data in early 2024,” said Bill Enright, CEO of Vaccitech.
  • Data from the first 58 women enrolled who reached their 6-month timepoint in the HPV001 placebo-controlled study were reviewed internally, and the trial will continue as planned to the 12-month primary endpoint. 
  • Also Read: Vaccitech’s Vaccine Induced Sustained Reductions In Hepatitis B Associated Antigens.
  • Immunogenicity results showed high responses, defined as an average greater than 1,000 spot-forming units per million peripheral blood mononuclear cells in an ELISPOT assay, especially to the E1, E2, and E6 antigens. 
  • VTP-200 was generally well-tolerated with no product-related grade 3 unsolicited events and no product-related SAEs. 
  • These interim data will be presented orally at the upcoming International Papillomavirus Conference in Washington D.C., taking place 17-21 April 2023.
  • Price Action: VACC shares are down 4.35% at $2.86 on the last check Monday.
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