Moderna, Generation Bio Collaborate To Develop Non-Viral Genetic Medicines

Moderna Inc (NASDAQ:MRNA) and Generation Bio Co (NASDAQ:GBIO) have collaborated to combine the application of each company’s platform by developing novel…
  • Moderna Inc (NASDAQ:MRNA) and Generation Bio Co (NASDAQ:GBIO) have collaborated to combine the application of each company’s platform by developing novel nucleic acid therapeutics, including those capable of reaching immune cells, to accelerate their respective pipelines of non-viral genetic medicines.
  • “Non-viral DNA therapeutics may offer durable, redosable, titratable genetic medicines to patients suffering from rare and prevalent diseases on a global scale,” said Phillip Samayoa, Chief Strategy Officer of Generation Bio.
  • Moderna may advance two immune cell programs using a jointly developed ctLNP to deliver ceDNA. 
  • In addition, Moderna may advance two liver programs, each of which may use a liver-targeted ctLNP developed by Generation Bio to deliver ceDNA. 
  • Moderna retains an option to license a third program for either immune cells or the liver.
  • Generation Bio will receive a $40 million upfront cash payment and a $36 million equity investment. 
  • Moderna will fund all collaboration work, including a research pre-payment. 
  • The agreement additionally gives Moderna the right to purchase additional Generation Bio shares.
  • Generation Bio is eligible for certain exclusivity fees, potential development and regulatory milestones, and royalties on products Moderna advances using ctLNP technology developed under the collaboration.
  • Price Action: GBIO shares are up 13.4% at $4.40 during the premarket session on the last check Thursday.
Total
0
Shares
Related Posts