Orgenesis Inc. (NASDAQ:ORGS) (“Orgenesis” or the “Company”), a global biotech company working to unlock the full potential of cell and gene therapies (CGTs), continues to grow the Point of Care (POCare) network and infrastructure of its advanced therapeutic services and facilities business through its subsidiary Octomera, by partnering with CGT Global, a biomedical company dedicated to advancing medical science and patient therapies. The two companies are collaborating to leverage CGT Global’s extensive network of CGT Clinics and Healthcare partnerships to expand commercialization of CGTs in California and other US locations. Resources will be aligned to place technology-agnostic Octomera Mobile Processing Units & Labs (OMPULs) for leukapheresis and the production of CAR-T and TILS products. The Company expects the footprint to grow as CGT Global partners with 32 hospitals today and anticipates partnering with over 200 hospitals by the end of 2024.
Since 2010, the CGT Global team has been dedicated to accelerating patient care and access by facilitating all components of the industry from R&D to clinical trials, drug manufacturing, and hospital partnerships. Their focus has remained acutely on the urgency of these products and therapies so that the landscape of medical care will be improved. CGT Global has created a bicoastal network of CGT Clinics in the US using state-of-the-art technology and specialized training in leukapheresis. Octomera will align with these sites and teams to help accelerate research and clinical trials into commercial products.
“The missions of CGT Global and Octomera are complementary. Both teams bring equity to the most cutting-edge medicines by decentralizing these complicated processes and capital-intensive expansions. At CGT Global, we have been creating a network of hospitals and CGT Clinics that reach far and wide with the goal of ensuring that all patients, regardless of location and financial status, can have access to the best medicines on the market,” Cate Spears, CEO at CGT Global said. “We have already successfully shortened the timeline to manufacture cells and leukapheresis products to rapidly accelerate clinical trials and access to patients quicker. Together with Octomera, we can take this progress one step further into accessible therapeutic GMP production, while also looking at other innovative solutions to bring therapies to patients in a way that has never been done before.”
“As we make more progress in the autologous advanced therapies space, and as hospitals are starting to seek first-line treatments to enhance quality of care and optimize resources, we see even greater value in decentralization. Over the past decade, our team has worked to engineer an agnostic, decentralized engineering approach for CGT production at the point of care, either in existing infrastructure or even outside of a building,” explained Vered Caplan, CEO of Octomera and Orgenesis. “Together with CGT Global, we will leverage their existing expertise, healthcare network and clinics to rapidly expand the support offering for point of care and advanced therapeutic production services. We are thrilled about the potential to overcome challenges with accessible end to end blood collection and cell production.”
CGT Global will provide expertise gained from being a leading provider of cellular manufacturing, biomedical therapeutic collections, and services through their existing network of CGT Clinics and hospital footprint. Octomera will provide services and support, as well as placement of agnostic OMPULs that are designed to standardize CGT production processes for quality and regulatory compliance across the globe at a fraction of the cost. The OMPULs will be designed based on the process, with consideration for regulatory compliance and quality management with centralized data and IT solutions. The OMPULs can be installed in six months within an existing structure or available outdoor space, and production capacity can easily be scaled through additional units. The interior can be purpose-built to include GMP-compliant production space as well as options for quality control labs. OMPULs can easily be added and stacked inside warehouse spaces. CGT Global has just built out a 52,000 sq ft warehouse facility in Reno, Nevada and with the OMPULs versatility, there are exciting times ahead for this great partnership.
To learn more about the partnership, or to talk about partnering, connect with the team at contact@octomera.com.
