Cellectis Announces Preliminary Clinical Data For UCART22 In ALL And UCART123 In AML

UCART22: anti-tumor activity observed in 60% (n=3) of patients at DL3 using FCA lymphodepletion UCART123: 25% (n=2) of patients at DL2 in the FCA arm achieved meaningful response; one patient
  • UCART22: anti-tumor activity observed in 60% (n=3) of patients at DL3 using FCA lymphodepletion
  • UCART123: 25% (n=2) of patients at DL2 in the FCA arm achieved meaningful response; one patient experienced a durable minimal residual disease (MRD)-negative complete response that continues beyond 12 months
  • BALLI-01 study (evaluating UCART22) now enrolling patients with product candidate manufactured in-house at DL2
  • AMELI-01 study (evaluating UCART123) now enrolling patients in a two-dose regimen arm at DL2

 

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