- Final data from Study 102 Dose Expansion show that radiotherapy-activated NBTXR3 was feasible and well tolerated in elderly patients with a high burden of comorbidity (n=56)
- Consistently high injected-lesion overall response rate of 81.8% and complete response rate of 63.6% in the evaluable population (n=44)
- Median duration of response in the NBTXR3-injected lesion was not reached, suggesting durable anti-tumor efficacy
- Median Progression Free of 16.9 months in the evaluable population per independent review committee at the final readout
- Median Overall Survival was 23.1 months in the evaluable population at the final readout
- Compared with historical data in a similar population showing mPFS of 9 months and mOS of 12 months, these results potentially strengthen the hypothesis and clarify next steps for the ongoing global, registrational Phase 3 study evaluating NBTXR3 for elderly patients with locally advanced head and neck cancer (NANORAY-312)
- Nanobiotix will host a conference call to discuss the data and take questions from participants on Thursday, October 5, 2023
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