Biomarker offers another companion diagnostic option to establish eligibility for FDA-approved drug ELAHERE®
SALT LAKE CITY, May 24, 2023 (GLOBE NEWSWIRE) — Myriad Genetics, Inc. (NASDAQ:MYGN), a leader in genetic testing and precision medicine, today announced the addition of Folate Receptor Alpha (FRα) to its Precise™ Oncology Solutions portfolio. The new biomarker adds another companion diagnostic option for providers to help guide treatment decisions for patients with ovarian cancer.
FRα is a biomarker commonly expressed in patients with ovarian cancer. FRα establishes patient eligibility for ELAHERE® (“mirvetuximab soravtansine-gynx”), the only FDA-approved drug indicated for patients who are FRα-positive and resistant to platinum-based chemotherapy. FRα is a newly recommended biomarker test included in the National Comprehensive Cancer Network treatment guidelines for ovarian cancer. According to the SORAYA study, 36% of patients screened were found to have high tumor FRα expression, representing a significant proportion of patients with ovarian cancer who could potentially benefit from MIRV-based therapy.
“FRα, alongside germline and homologous recombination deficiency status, can be a powerful biomarker for patients with ovarian cancer to create a comprehensive treatment plan,” said Ramez N. Eskander, associate professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at UC San Diego School of Medicine. “Patients will benefit from Myriad’s addition of FRα testing to their Precise Oncology Solutions portfolio to help improve outcomes for this patient group.”
FRα is available immediately and can be ordered alongside other companion diagnostic test offerings through the Myriad ordering portal. For a streamlined workflow and quicker path to making treatment decisions, oncologists can receive germline, HRD, FRα biomarker and tumor testing results from a single laboratory.
“The expansion of our portfolio with FRα highlights our commitment to continually growing and innovating to support oncologists with comprehensive, data-driven genetic insights that can better inform treatment decisions for their patients,” said Michael Lyons, general manager of Oncology, Myriad Genetics.