- HC Wainwright has initiated Theseus Pharmaceuticals Inc (NASDAQ:THRX) with a Buy rating and a price target of $22 (310% upside).
- The analysts see gastrointestinal stromal tumors (GISTs) treatment space reigniting with the entrance of a Theseus’ pan-KIT inhibitor THE-630, with a high likelihood of 5L approval with earlier line potential.
- The analysts believe THE-630 can adequately tackle resistance in GIST by using dynamic molecular touchpoints that aim to ensure retention of inhibition.
- Related: Analysts See Huge Upside In This Newly Listed Biopharma Stock.
- HC Wainwright believes proprietary predictive resistance assay (PRA), a novel cell-based drug screening platform sets Theseus’ approach apart.
- THE-630 is currently being evaluated in a Phase 1 trial for GIST, with an initial readout expected in 1H23.
- The analysts are optimistic about THE-630 demonstrating preliminary objective response rate signals based on THE-630’s performance in preclinical studies.
- The analysts note that Theseus’ PRA platform has already generated multiple promising tyrosine kinase inhibitor candidates for its EGFRi program, with a planned final nomination in 3Q22.
- Price Action: THRX shares are down 1.99% at $5.42 during the market session on the last check Friday.
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